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Internal Medicine / Gastroenterology

William Frederick Stenson, MD

Current Position
Dr. Nicholas V. Costrini Professor of Gastroenterology & Inflammatory Bowel Disease, Division of Gastroenterology

Specialty Areas
Gastrointestinal Oncology
Inflammatory Bowel Disease

Patients Seen At
Center for Advanced Medicine
GI Center
4921 Parkview Place, C, 8
St. Louis, MO  63110
Fax:   314-362-9035
View Floor Map  View Campus Map   View Driving Directions

Mailing Address
Washington University School of Medicine, Division of Gastroenterology
660 South Euclid Avenue, Campus Box 8124
St. Louis, MO  63110

Areas of Clinical Interest
Gastroenterology, inflammatory bowel disease, ulcerative colitis, Crohn’s disease, celiac disease

Board Certification
Internal Medicine -- Certified
Gastroenterology -- Certified

Medical Education
B.S.: Providence College, Providence, Rhode Island, 1967
Medical Degree: Washington University School of Medicine, St Louis, Missouri, 1971
Residency: Internal Medicine, Barnes-Jewish Hospital, St. Louis, Missouri, 1976
Fellowship: Gastroenterology, Washington University School of Medicine, St Louis, Missouri, 1978
Hospital Affiliations
Barnes-Jewish Hospital

Selected or Recent Journal Articles
Thaker AI, Rao MS, Bishnupuri KS, Kerr TA, Foster L, Marinshaw JM, Newberry RD, Stenson WF, Ciorba MA. IDO1 metabolites activate β-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice. Gastroenterology. 2013 Aug;145(2):416-25.e1-4.

Khurana SS, Riehl TE, Moore BD, Fassan M, Rugge M, Romero-Gallo J, Noto J, Peek RM Jr, Stenson WF, Mills JC. J Biol Chem. 2013 May 31;288(22):16085-97.

Riehl TE, Ee X, Stenson WF. Hyaluronic acid regulates normal intestinal and colonic growth in mice. Am J Physiol Gastrointest Liver Physiol. 2012 Aug 1;303(3):G377-88.

Ciorba MGupta NK, Thaker AI, Kanuri N, Riehl TE, Rowley CW, Stenson WF, Ciorba MA.
Serum analysis of tryptophan catabolism pathway: correlation with Crohn's disease activity. Inflamm Bowel Dis. 2012 Jul;18(7):1214-20.

A, Riehl TE, Rao MS, Moon C, Ee X, Nava GM, Walker MR, Marinshaw JM, Stappenbeck TS, Stenson WF. Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/cyclo-oxygenase-2-dependent manner. Gut. 2012 Jun;61(6):829-38.

Riehl TE, Foster L, Stenson WF. Hyaluronic acid is radioprotective in the intestine through a TLR4 and COX-2-mediated mechanism. Am J Physiol Gastrointest Liver Physiol. 2012 Feb 1;302(3):G309-16.

Riehl TE, He L, Zheng L, Greco S, Tollefsen DM, Stenson WF. COX-1(+/-)COX-2(-/-) genotype in mice is associated with shortened time to carotid artery occlusion through increased PAI-1. J Thromb Haemost. 2011 Feb;9(2):350-60.

Ciorba MA, Bettonville EE, McDonald KG, Metz R, Prendergast GC, Newberry RD, Stenson WF. Induction of IDO-1 by immunostimulatory DNA limits severity of experimental colitis. J Immunol. 2010 Apr 1;184(7):3907-16.

Stenson WF. Hyaluronic acid and intestinal inflammation. Curr Opin Gastroenterol. 2010 Mar;26(2):85-7.

Walker MR, Brown SL, Riehl TE, Stenson WF, Stappenbeck TS. Growth factor regulation of prostaglandin-endoperoxide synthase 2 (Ptgs2) expression in colonic mesenchymal stem cells. J Biol Chem. 2010 Feb 12;285(7):5026-39.

Zheng L, Riehl TE, Stenson WF. Regulation of colonic epithelial repair in mice by Toll-like receptors and hyaluronic acid. Gastroenterology. 2009 Dec;137(6):2041-51.

Ciorba MA, Stenson WF. Probiotic therapy in radiation-induced intestinal injury and repair. Ann N Y Acad Sci. 2009 May;1165:190-4.

Katona BW, Anant S, Covey DF, Stenson WF. Characterization of enantiomeric bile acid-induced apoptosis in colon cancer cell lines. J Biol Chem. 2009 Jan 30;284(5):3354-64.

Stenson WF. What is the function of cyclooxygenases in the normal and inflamed intestine? Inflamm Bowel Dis. 2008 Oct;14 Suppl 2:S104-5.

Alford SK, Longmore GD, Stenson WF, Kemper C. CD46-induced immunomodulatory CD4+ T cells express the adhesion molecule and chemokine receptor pattern of intestinal T cells. J Immunol. 2008 Aug 15;181(4):2544-55.

For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr. William Stenson.

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Copyright 2015 Washington University School of Medicine
Copyright 2015 Washington University School of Medicine