William Frederick Stenson, MD
Current Position
Dr. Nicholas V. Costrini Professor of Gastroenterology & Inflammatory Bowel Disease, Division of Gastroenterology
Specialty Areas
Gastroenterology
Gastrointestinal Oncology
Inflammatory Bowel Disease
Mailing Address
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Washington University School of Medicine, Division of Gastroenterology
660 South Euclid Avenue, Campus Box 8124
St. Louis,
MO
63110
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Areas of Clinical Interest
Gastroenterology, inflammatory bowel disease, ulcerative colitis, Crohn’s disease, celiac disease
Board Certification
Internal Medicine
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Certified
Gastroenterology
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Certified
Medical Education
B.S.: Providence College, Providence, Rhode Island, 1967
Medical Degree: Washington University School of Medicine, St Louis, Missouri, 1971
Residency: Internal Medicine, Barnes-Jewish Hospital, St. Louis, Missouri, 1976
Fellowship: Gastroenterology, Washington University School of Medicine, St Louis, Missouri, 1978
Hospital Affiliations
Barnes-Jewish Hospital
Selected or Recent Journal Articles
Sundaresan, S, Shahid, R., Riehl, T.E., Chandra, R., Nassir, F., Stenson, W.F., Liddle, R.A., and Abumrad, N.A. CD36- dependent signaling mediates fatty acid induced gut release of secretin and cholecystokinin. FASEB . Journal, in press.
Riehl TE, Ee,X, Stenson WF. Hyaluronic Acid Regulates Normal Intestinal and Colonic Growth in Mice. Am J Physiol (Gastrointest Liver Physiol). 2012; 303(3):G377-88
Ciorba M, Riehl TE, Rao S, Moon C, Ee X, Nava G, Walker M, Marinshaw J, Stappenbeck T, Stenson WF. Lactobacillus probiotic protects intestinal epithelium from radiation injury in TLR-2/cyclooxygenase-2 dependent manner. GUT 2012;61(6):829-838.
Riehl TE, Foster L, Stenson WF. Hyaluronic Acid is Radioprotective in the Intestine through a TLR-4 and COX-2 Mediated Mechanism. Am J Physiol . 2011; 302:G309-G316.
Gupta N, Thaker A, Kanuri N, Riehl T, Rowley C, Stenson WF, Ciorba MA. Serum Analysis of Tryptophan Catabolism Pathway: Correlation with Crohn’s Disease Activity. Inflamm Bowel Dis. 2011 Aug 5.
Riehl TE, He L, Zheng L, Greco S, Tollefsen D, Stenson WF. COX-1+/-COX-2-/- genotype in mice is associated with shortened time to carotid artery occlusion through increased PAI-1. Journal of Thrombosis Haemostasis.9:1-10;2011
Ciorba MA, Bettonville EE, McDonald K, Metz R, Prendergast C, Newberry RD, Stenson, WF. Induction of IDO-1 by Immunostimulatory DNA Limits Severity of Experimental Colitis. J. Immunol 184;3907-3916:2010.
Walker MR, Brown SL, Riehl TE, Stenson WF, Stappenbeck TS. Growth factor regulation of prostaglandin-endoperoxide synthase 2 (PTGS2) expression in colonic mesenchymal stem cells. J Biol Chem. 285(7);5026-5039:2010
Katona BW, Anant S, Stenson WF. Characterization of enantiomeric bile acid-induced apoptosis in colon cancer cell lines. Journal of Biological Chemistry 284(5):3354-64,2009
Ciorba M, Stenson WF. Probiotic therapy in radiation-induced intestinal injury and repair. Ann NY Acad Sci.1165:190-4,2009
Zheng L, Riehl T, Stenson WF. Regulation of Colonic Epithelial Repair in Mice by Toll-like Receptors and Hyaluronic Acid. Gastroenterology. 137(6);2041-51:2009.
Alford SK, Longmore GD, Stenson WF, Kemper C. CD46-induced immunomodulatory CD4+T cells express the adhesion molecule and chemokines receptor pattern of intestinal T cells. Journal of Immunology. 15;181(4):2544-55: 2008
Katona BW, Rath NP, Anant S, Stenson WF, Covey DF. Enantiomeric deoxycholic acid: total synthesis, characterization, and preliminary toxicity toward colon cancer cell lines. Journal of Organic Chemistry. 72(24):9298-307;2007
Brown SL, Riehl TE, Walker MR, Geske MJ, Doherty JM, Stenson WF, Stappenbeck TS. Myd88- dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury. In press. J. Clin. Invest,117:258-69;2007
James DG, Stone CD, Wang HL, Stenson WF. Reactive hemophagocytic syndrome complicating the treatment of inflammatory bowel disease. Inflammatory Bowel Diseases. 12:573-80, 2006.